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| 03/12/2022 | 13:00 | Bahlinger SC | - | SSV Ulm 1846 | 0:0 (0:0) | |
| 13:00 | Eintracht Trier | - | VfB Stuttgart II | 0:5 (0:1) | ||
| 13:00 | Wormatia Worms | - | FC-Astoria Walldorf | 0:1 (0:1) | ||
| 13:00 | 1899 Hoffenheim II | - | Kickers Offenbach | 3:1 (1:0) | ||
| 13:00 | Rot-Weiß Koblenz | - | Hessen Kassel | 2:1 (1:0) | ||
| 13:00 | FSV Frankfurt | - | FC 08 Homburg | 1:1 (0:0) | ||
| 13:00 | SGV Freiberg | - | TSG Balingen | 1:3 (0:1) | ||
| 13:00 | SG Barockstadt Fulda-Lehnerz | - | VfR Aalen | 5:0 (3:0) | ||
| 13:00 | 1. FSV Mainz 05 II | - | TSV Steinbach Haiger | 1:1 (0:0) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSV Ulm 1846 | 19 | 12 | 6 | 1 | 35:12 | 23 | 42 |
| 2 |
|
TSV Steinbach Haiger | 19 | 10 | 5 | 4 | 43:23 | 20 | 35 |
| 3 |
|
TSG Balingen | 19 | 10 | 5 | 4 | 28:19 | 9 | 35 |
| 4 |
|
FC 08 Homburg | 19 | 10 | 4 | 5 | 37:23 | 14 | 34 |
| 5 |
|
Kickers Offenbach | 19 | 10 | 4 | 5 | 36:22 | 14 | 34 |
| 6 |
|
1899 Hoffenheim II | 19 | 10 | 4 | 5 | 39:29 | 10 | 34 |
| 7 |
|
SG Barockstadt Fulda-Lehnerz | 19 | 7 | 7 | 5 | 32:24 | 8 | 28 |
| 8 |
|
VfB Stuttgart II | 19 | 7 | 7 | 5 | 31:23 | 8 | 28 |
| 9 |
|
FSV Frankfurt | 19 | 8 | 3 | 8 | 31:27 | 4 | 27 |
| 10 |
|
1. FSV Mainz 05 II | 19 | 8 | 3 | 8 | 32:31 | 1 | 27 |
| 11 |
|
Bahlinger SC | 19 | 8 | 2 | 9 | 21:28 | -7 | 26 |
| 12 |
|
FC-Astoria Walldorf | 19 | 7 | 4 | 8 | 27:39 | -12 | 25 |
| 13 |
|
SGV Freiberg | 19 | 4 | 6 | 9 | 22:35 | -13 | 18 |
| 14 |
|
Hessen Kassel | 19 | 4 | 5 | 10 | 18:31 | -13 | 17 |
| 15 |
|
Wormatia Worms | 19 | 4 | 4 | 11 | 17:32 | -15 | 16 |
| 16 |
|
VfR Aalen | 19 | 7 | 3 | 9 | 24:32 | -8 | 15 |
| 17 |
|
Eintracht Trier | 19 | 3 | 4 | 12 | 17:36 | -19 | 13 |
| 18 |
|
Rot-Weiß Koblenz | 19 | 2 | 4 | 13 | 12:36 | -24 | 10 |
| Promotion | |
| Relegation |
