| 1. Round | 13/08/2021 | SSV Ulm 1846 | - | FSV Frankfurt | 3:3 | ||||
| 3. Round | 24/08/2021 | SSV Ulm 1846 | - | SV 07 Elversberg | 4:2 | ||||
| 4. Round | 28/08/2021 | Kickers Offenbach | - | SSV Ulm 1846 | 1:2 |  |
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| 10. Round | 28/09/2021 | SSV Ulm 1846 | - | 1. FSV Mainz 05 II | 0:2 | ||||
| 11. Round | 02/10/2021 | TSV Schott Mainz | - | SSV Ulm 1846 | 0:1 | ||||
| 14. Round | 22/10/2021 | SSV Ulm 1846 | - | TSG Balingen | 1:2 | ||||
| 17. Round | 06/11/2021 | TSV Steinbach Haiger | - | SSV Ulm 1846 | 0:3 | ||||
| 22. Round | 12/12/2021 | SV 07 Elversberg | - | SSV Ulm 1846 | 1:0 |
Germany