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| 1st(1st leg) | Hamburger SV | - | Hertha Zehlendorf | 1:7 | ||
| 2nd (2nd leg) | Hertha Zehlendorf | - | Hamburger SV | 0:2 | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: Hertha Zehlendorf | ||||
| 1st(1st leg) | Arminia Hannover | - | 1. FC Köln | 2:2 | ||
| 2nd (2nd leg) | 1. FC Köln | - | Arminia Hannover | 2:1 | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: 1. FC Köln | ||||
| 1st(1st leg) | Freiburger FC | - | 1. FC Saarbrücken | 6:0 | ||
| 2nd (2nd leg) | 1. FC Saarbrücken | - | Freiburger FC | 3:2 | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: Freiburger FC | ||||
| 1st(1st leg) | Stuttgarter Kickers | - | OSC Bremerhaven | 0:2 | ||
| 2nd (2nd leg) | OSC Bremerhaven | - | Stuttgarter Kickers | 0:1 | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: OSC Bremerhaven | ||||
| 1st(1st leg) | FC Augsburg | - | MSV Duisburg | 1:2 | ||
| 2nd (2nd leg) | MSV Duisburg | - | FC Augsburg | 3:3 | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: MSV Duisburg | ||||
| 1st(1st leg) | 1. FSV Mainz 05 | - | EGC Wirges | 2:2 | ||
| 2nd (2nd leg) | EGC Wirges | - | 1. FSV Mainz 05 | 5:4 pso | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: EGC Wirges | ||||
| 1st(1st leg) | Borussia Dortmund | - | Waldhof Mannheim | 2:2 | ||
| 2nd (2nd leg) | Waldhof Mannheim | - | Borussia Dortmund | 1:0 | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: Waldhof Mannheim | ||||
| 1st(1st leg) | Eintracht Frankfurt | - | VfB Lübeck | 2:0 | ||
| 2nd (2nd leg) | VfB Lübeck | - | Eintracht Frankfurt | 2:4 | ||
| 1st(1st leg): 04/06/1978 | 2nd (2nd leg): 11/06/1978 | Winner: Eintracht Frankfurt | ||||
