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| 1st(1st leg) | Fortuna Düsseldorf | - | Werder Bremen | 1:0 | ||
| 2nd (2nd leg) | Werder Bremen | - | Fortuna Düsseldorf | 2:3 pso | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: Fortuna Düsseldorf | ||||
| 1st(1st leg) | Concordia Hamburg | - | Arminia Hannover | 2:2 | ||
| 2nd (2nd leg) | Arminia Hannover | - | Concordia Hamburg | 3:2 | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: Arminia Hannover | ||||
| 1st(1st leg) | 1. FC Köln | - | Holstein Kiel | 5:0 | ||
| 2nd (2nd leg) | Holstein Kiel | - | 1. FC Köln | 2:3 | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: 1. FC Köln | ||||
| 1st(1st leg) | Blau-Weiß 90 Berlin | - | FC Schalke 04 | 3:1 | ||
| 2nd (2nd leg) | FC Schalke 04 | - | Blau-Weiß 90 Berlin | 6:1 | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: FC Schalke 04 | ||||
| 1st(1st leg) | SG 99 Andernach | - | Waldhof Mannheim | 0:3 | ||
| 2nd (2nd leg) | Waldhof Mannheim | - | SG 99 Andernach | 1:1 | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: Waldhof Mannheim | ||||
| 1st(1st leg) | Eintracht Frankfurt | - | FC Tailfingen | 3:0 | ||
| 2nd (2nd leg) | FC Tailfingen | - | Eintracht Frankfurt | 0:5 | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: Eintracht Frankfurt | ||||
| 1st(1st leg) | TSV 1860 München | - | 1. FC Kaiserslautern | 1:1 | ||
| 2nd (2nd leg) | 1. FC Kaiserslautern | - | TSV 1860 München | 1:0 | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: 1. FC Kaiserslautern | ||||
| 1st(1st leg) | Offenburger FV | - | SV Preussen Merchweiler | 1:2 | ||
| 2nd (2nd leg) | SV Preussen Merchweiler | - | Offenburger FV | 4:2 pso | ||
| 1st(1st leg): 01/06/1980 | 2nd (2nd leg): 08/06/1980 | Winner: SV Preussen Merchweiler | ||||
