1st(1st leg) FC København - APOEL Nikosia 1:0 (1:0)
2nd (2nd leg) APOEL Nikosia - FC København 1:1 (0:0)
1st(1st leg): 16/08/2016 19:45 2nd (2nd leg): 24/08/2016 19:45 Winner: FC København
1st(1st leg) Dinamo Zagreb - RB Salzburg 1:1 (0:0)
2nd (2nd leg) RB Salzburg - Dinamo Zagreb 1:2 (1:0, 1:1) aet
1st(1st leg): 16/08/2016 19:45 2nd (2nd leg): 24/08/2016 19:45 Winner: Dinamo Zagreb
1st(1st leg) Steaua Bucureşti - Manchester City 0:5 (0:2)
2nd (2nd leg) Manchester City - Steaua Bucureşti 1:0 (0:0)
1st(1st leg): 16/08/2016 19:45 2nd (2nd leg): 24/08/2016 19:45 Winner: Manchester City
1st(1st leg) AFC Ajax - FK Rostov 1:1 (1:1)
2nd (2nd leg) FK Rostov - AFC Ajax 4:1 (1:0)
1st(1st leg): 16/08/2016 19:45 2nd (2nd leg): 24/08/2016 19:45 Winner: FK Rostov
1st(1st leg) BSC Young Boys - Bor. Mönchengladbach 1:3 (0:1)
2nd (2nd leg) Bor. Mönchengladbach - BSC Young Boys 6:1 (3:0)
1st(1st leg): 16/08/2016 19:45 2nd (2nd leg): 24/08/2016 19:45 Winner: Bor. Mönchengladbach
1st(1st leg) PFC Ludogorets Razgrad - Viktoria Plzeň 2:0 (0:0)
2nd (2nd leg) Viktoria Plzeň - PFC Ludogorets Razgrad 2:2 (1:1)
1st(1st leg): 17/08/2016 19:45 2nd (2nd leg): 23/08/2016 19:45 Winner: PFC Ludogorets Razgrad
1st(1st leg) Celtic FC - Hapoel Be'er Sheva 5:2 (3:0)
2nd (2nd leg) Hapoel Be'er Sheva - Celtic FC 2:0 (1:0)
1st(1st leg): 17/08/2016 19:45 2nd (2nd leg): 23/08/2016 19:45 Winner: Celtic FC
1st(1st leg) Dundalk FC - Legia Warszawa 0:2 (0:0)
2nd (2nd leg) Legia Warszawa - Dundalk FC 1:1 (0:1)
1st(1st leg): 17/08/2016 19:45 2nd (2nd leg): 23/08/2016 19:45 Winner: Legia Warszawa
1st(1st leg) FC Porto - AS Roma 1:1 (0:1)
2nd (2nd leg) AS Roma - FC Porto 0:3 (0:1)
1st(1st leg): 17/08/2016 19:45 2nd (2nd leg): 23/08/2016 19:45 Winner: FC Porto
1st(1st leg) Villarreal CF - AS Monaco 1:2 (1:1)
2nd (2nd leg) AS Monaco - Villarreal CF 1:0 (0:0)
1st(1st leg): 17/08/2016 19:45 2nd (2nd leg): 23/08/2016 19:45 Winner: AS Monaco