1st(1st leg) APOEL Nikosia - Qarabağ FK 1:2 (0:0)
2nd (2nd leg) Qarabağ FK - APOEL Nikosia 0:2 (0:1)
1st(1st leg): 06/08/2019 18:00 2nd (2nd leg): 13/08/2019 17:30 Winner: APOEL Nikosia
1st(1st leg) PAOK Saloniki - AFC Ajax 2:2 (2:1)
2nd (2nd leg) AFC Ajax - PAOK Saloniki 3:2 (1:1)
1st(1st leg): 06/08/2019 18:00 2nd (2nd leg): 13/08/2019 19:30 Winner: AFC Ajax
1st(1st leg) Dinamo Zagreb - Ferencvárosi TC 1:1 (1:0)
2nd (2nd leg) Ferencvárosi TC - Dinamo Zagreb 0:4 (0:1)
1st(1st leg): 06/08/2019 19:00 2nd (2nd leg): 13/08/2019 19:00 Winner: Dinamo Zagreb
1st(1st leg) Club Brugge KV - Dinamo Kiev 1:0 (1:0)
2nd (2nd leg) Dinamo Kiev - Club Brugge KV 3:3 (1:1)
1st(1st leg): 06/08/2019 19:30 2nd (2nd leg): 13/08/2019 18:30 Winner: Club Brugge KV
1st(1st leg) Crvena Zvezda - FC København 1:1 (1:0)
2nd (2nd leg) FC København - Crvena Zvezda 6:7 (1:1, 1:1, 1:1) pso
1st(1st leg): 06/08/2019 19:45 2nd (2nd leg): 13/08/2019 19:00 Winner: Crvena Zvezda
1st(1st leg) FK Krasnodar - FC Porto 0:1 (0:0)
2nd (2nd leg) FC Porto - FK Krasnodar 2:3 (0:3)
1st(1st leg): 07/08/2019 18:00 2nd (2nd leg): 13/08/2019 20:00 Winner: FK Krasnodar
1st(1st leg) İstanbul Başakşehir F.K. - Olympiakos Piräus 0:1 (0:0)
2nd (2nd leg) Olympiakos Piräus - İstanbul Başakşehir F.K. 2:0 (0:0)
1st(1st leg): 07/08/2019 18:45 2nd (2nd leg): 13/08/2019 19:30 Winner: Olympiakos Piräus
1st(1st leg) CFR Cluj - Celtic FC 1:1 (1:1)
2nd (2nd leg) Celtic FC - CFR Cluj 3:4 (0:1)
1st(1st leg): 07/08/2019 19:00 2nd (2nd leg): 13/08/2019 19:45 Winner: CFR Cluj
1st(1st leg) FC Basel - LASK 1:2 (0:0)
2nd (2nd leg) LASK - FC Basel 3:1 (0:0)
1st(1st leg): 07/08/2019 19:00 2nd (2nd leg): 13/08/2019 19:30 Winner: LASK
1st(1st leg) NK Maribor - Rosenborg BK 1:3 (0:0)
2nd (2nd leg) Rosenborg BK - NK Maribor 3:1 (0:1)
1st(1st leg): 07/08/2019 19:15 2nd (2nd leg): 13/08/2019 18:00 Winner: Rosenborg BK