1st(1st leg) CFR Cluj - Slavia Praha 0:1 (0:1)
2nd (2nd leg) Slavia Praha - CFR Cluj 1:0 (0:0)
1st(1st leg): 20/08/2019 20:00 2nd (2nd leg): 28/08/2019 20:00 Winner: Slavia Praha
1st(1st leg) APOEL Nikosia - AFC Ajax 0:0 (0:0)
2nd (2nd leg) AFC Ajax - APOEL Nikosia 2:0 (1:0)
1st(1st leg): 20/08/2019 20:00 2nd (2nd leg): 28/08/2019 20:00 Winner: AFC Ajax
1st(1st leg) LASK - Club Brugge KV 0:1 (0:1)
2nd (2nd leg) Club Brugge KV - LASK 2:1 (0:0)
1st(1st leg): 20/08/2019 20:00 2nd (2nd leg): 28/08/2019 20:00 Winner: Club Brugge KV
1st(1st leg) Dinamo Zagreb - Rosenborg BK 2:0 (2:0)
2nd (2nd leg) Rosenborg BK - Dinamo Zagreb 1:1 (1:0)
1st(1st leg): 21/08/2019 20:00 2nd (2nd leg): 27/08/2019 20:00 Winner: Dinamo Zagreb
1st(1st leg) BSC Young Boys - Crvena Zvezda 2:2 (1:1)
2nd (2nd leg) Crvena Zvezda - BSC Young Boys 1:1 (0:0)
1st(1st leg): 21/08/2019 20:00 2nd (2nd leg): 27/08/2019 20:00 Winner: Crvena Zvezda
1st(1st leg) Olympiakos Piräus - FK Krasnodar 4:0 (1:0)
2nd (2nd leg) FK Krasnodar - Olympiakos Piräus 1:2 (1:1)
1st(1st leg): 21/08/2019 20:00 2nd (2nd leg): 27/08/2019 20:00 Winner: Olympiakos Piräus