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| 02/12/2022 | 11:00 | FC Schalke 04 II | - | 1. FC Köln II | 5:0 (3:0) | |
| 18:30 | Fortuna Köln | - | Rot Weiss Ahlen | 2:1 (2:0) | ||
| 03/12/2022 | 13:00 | 1. FC Kaan-Marienborn | - | SV 19 Straelen | 2:1 (0:1) | |
| 13:00 | Rot-Weiß Oberhausen | - | Bor. Mönchengladbach II | 1:0 (0:0) | ||
| 13:00 | 1. FC Düren | - | Alemannia Aachen | 1:1 (0:1) | ||
| 13:00 | Fortuna Düsseldorf II | - | 1. FC Bocholt | 0:0 (0:0) | ||
| 13:00 | Preußen Münster | - | SC Wiedenbrück | 2:0 (0:0) | ||
| 13:00 | Wuppertaler SV | - | SG Wattenscheid 09 | 4:2 (2:0) | ||
| 13:00 | SV Rödinghausen | - | SV Lippstadt 08 | 1:2 (0:2) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 19 | 14 | 2 | 3 | 50:20 | 30 | 44 |
| 2 |
|
Wuppertaler SV | 19 | 10 | 5 | 4 | 37:23 | 14 | 35 |
| 3 |
|
Bor. Mönchengladbach II | 19 | 9 | 6 | 4 | 32:22 | 10 | 33 |
| 4 |
|
Alemannia Aachen | 19 | 9 | 6 | 4 | 30:22 | 8 | 33 |
| 5 |
|
1. FC Kaan-Marienborn | 19 | 9 | 4 | 6 | 28:27 | 1 | 31 |
| 6 |
|
FC Schalke 04 II | 19 | 8 | 6 | 5 | 40:24 | 16 | 30 |
| 7 |
|
SV Lippstadt 08 | 19 | 9 | 3 | 7 | 33:33 | 0 | 30 |
| 8 |
|
Rot-Weiß Oberhausen | 19 | 8 | 5 | 6 | 32:32 | 0 | 29 |
| 9 |
|
Fortuna Köln | 19 | 8 | 5 | 6 | 23:26 | -3 | 29 |
| 10 |
|
SV Rödinghausen | 19 | 8 | 4 | 7 | 32:19 | 13 | 28 |
| 11 |
|
SC Wiedenbrück | 19 | 6 | 5 | 8 | 28:23 | 5 | 23 |
| 12 |
|
Fortuna Düsseldorf II | 19 | 7 | 2 | 10 | 32:39 | -7 | 23 |
| 13 |
|
1. FC Düren | 19 | 7 | 2 | 10 | 23:34 | -11 | 23 |
| 14 |
|
Rot Weiss Ahlen | 19 | 5 | 5 | 9 | 31:38 | -7 | 20 |
| 15 |
|
1. FC Bocholt | 19 | 5 | 5 | 9 | 27:41 | -14 | 20 |
|
1. FC Köln II | 19 | 5 | 5 | 9 | 27:41 | -14 | 20 | |
| 17 |
|
SG Wattenscheid 09 | 19 | 4 | 3 | 12 | 27:51 | -24 | 15 |
| 18 |
|
SV 19 Straelen | 19 | 2 | 3 | 14 | 12:29 | -17 | 9 |
| Promotion | |
| Relegation | |
| Relegation |
